Acid–base titrations are volumetric analytical methods based on the neutralization reaction between an acid and a base. The end point is detected using suitable indicators.
Acid–base indicators are weak organic acids or bases that exhibit different colors in acidic and basic media. Common indicators include methyl orange, phenolphthalein, and bromothymol blue.
The choice of indicator depends on the nature of the acid and base involved and the pH at the equivalence point of the titration.
Acid–base titrations are widely used for the assay of pharmaceutical substances, estimation of alkalinity or acidity, and quality control of raw materials.